Radioiodine avid adenomatous colon polyp in a post-treatment whole body radioiodine scan

A 47 year old female with papillary thyroid carcinoma was referred to our department for post-treatment whole body iodine scanning. The acquired images revealed a focal zone of intense radiotracer uptake in the right lower quadrant of the abdomen. SPECT/CT fused slices showed a focal zone of the radioiodine (131I) uptake in the right colon wall. Colonoscopy revealed a pedunculated polyp in the right colon. Eventually, a benign adenomatous polyp was confirmed by histopathologic assessment. To the extent of our knowledge, this is the first case of large bowel polyp demonstrating radioiodine uptake, reported in the literature.